| Reference # |
Patent
Status |
Category |
Description |
| 2008-016 |
None
|
Research Tools |
Anti-SINA/SIAH Monoclonal Antibodies & Related Know-How
Four mouse anti-SINA/SIAH monoclonal antibodies are available for licensing. Details are as follows. Two ...
|
| 2008-036 |
Pending
|
Medical Devices |
Artifact Reduction System (ARS) for Ultrasound Coblation Procedures
Coblation devices are currently being employed to débride diseased tendons and other soft tissue via open and ...
|
| 2008-037 |
None
|
Medical Devices |
Ultrasound Guided Balloon Dilator (UGBD)
The UGBD is a versatile medical device utilized to percutaneously dilate soft tissue regions in the body. ...
|
| 2007-003 |
None
|
Research Tools |
A New Cytochrome P450 2D6 (CYP2D6) Allele
A new allele resulting from a crossover between two genes known as cytochrome P450 2D6 (CYP2D6) and the ...
|
| 2007-005 |
Pending
|
Diagnostics |
Human Catechol O-Methyltransferase Gene Polymorphisms and Risk for Breast Cancer
Two single nucleotide polymorphism (SNPs) within the COMT gene have been identified as potential biomarkers ...
|
| 2007-006 |
Pending
|
Software |
Axial Centerline Following for Display of CT Colonography Images
This invention consists of a novel display technique for CT colonography data. It is based on automatic ...
|
| 2007-007 |
Pending
|
Software |
Oblique Centerline Following for Display of CT Colonography Images
This invention consists of a novel display technique for CT colonography data. It is based on automatic ...
|
| 2007-008 |
Pending
|
Software |
Electronic Stool Subtraction Using Quadratic Regression and Intelligent Morphology
CT colonography (CTC) is being extensively studied for its potential value in colon examinations. Like ...
|
| 2007-009 |
Pending
|
Software |
Simultaneous Dual Window/Level Settings for Improved Viewing of CT Colongraphy Images
Currently, radiologists interpreting CT colonography exams find it most efficient to view colons primarily in ...
|
| 2007-016 |
None
|
Research Tools |
Transgenic Mouse Expressing P1 Artificial Chromosome (PAC) Containing the Entire Human Alpha-Synuclein (SNCA) Gene
Tansgenic mouse that over-expresses the human alpha-synuclein gene, under the control of its endogenous human ...
|
| 2007-027 |
None
|
Research Tools |
LRRK2 BAC Transgenic Mice: A Model of Parkinsonism
Mice that over-express the human wild-type and mutant leucine-rich repeat kinase 2 gene (LRRK2)....
|
| 2007-032 |
Pending
|
Diagnostics |
Novel Cytochrome P450 (CYP) 2D6 Gene and CYP2D7 Pseudogene Arrangements and Tests for Detection of These Newly Discovered Gene Arrangements
The CYP2D6 gene makes a protein that metabolizes drugs. This gene is highly variable. It can have different ...
|
| 2007-033 |
Pending
|
Diagnostics |
Determination of the Phase of Duplicated CYP2D6 Alleles
These methods enable determination of the phase of duplicated of CYP2D6 alleles using an allele specific ...
|
| 2007-039 |
None
|
Medical Devices |
Adherent Thoracolumbar Plate and Rod Spine Stabilization Implant
A spinal implant composed of a locking screw-plate and rod used to stabilize the anterior human spine. An ...
|
| 2007-042 |
Pending
|
Therapeutics |
Abeta42 Lowering Agents that Inhibit Abeta Aggregation
Aggregation of Abeta42 is proposed to cause Alzheimers disease. Lowering Abeta42 production and preventing ...
|
| 2007-043 |
Pending
|
Therapeutics |
Enodgenous Wild Type BRI Peptides as Potential Therapeutic Compound for the Treatment and Prevention of AD
Amyloid beta peptide (Abeta) accumulation within senile plaques, cerebral blood vessels walls, and diffuse ...
|
| 2007-050 |
Pending
|
Research Tools |
Establishment and Characterization of an Immunoglobulin Lambda Secreting Cell Line from AL Amyloidsis
The ALMC-1 and ALMC-2 cell lines were established from samples before and after peripheral blood stem cell ...
|
| 2007-055 |
Pending
|
Therapeutics |
A Novel Synthetic Natriuretic Peptide, CU-NP
Heart failure is a major public health problem and is the leading cause of hospitalization in adults over 65 ...
|
| 2007-063 |
None
|
Therapeutics |
Tau Multimers as Therapeutic Target in Tauopathies
We define biochemical tau species, called tau multimers, in vivo both in mouse models of tauopathies and ...
|
| 2007-077 |
Pending
|
Therapeutics |
Selective and Irreversible Inhibitors of Insect AChEs for Pest Control: a New-Generation of Human-Safe and Effective Pesticides
This invention relates to invertebrate and insect-specific acetylcholinesterase (AChE) inhibitors, as well as ...
|
| 2007-079 |
Pending
|
Research Tools |
Staphylococcus Lugdunensis Hypothetical Glycosyl Hydrolase
The Staphylococcus lugdunensis hypothetical glycosyl hydrolase is the predicted gene product of an open ...
|
| 2007-088 |
Pending
|
Medical Devices |
Multi-Planar EUS Transducer
This echoendoscope would include a transducer (of variable shapes) with multiple crystal of which some ...
|
| 2007-091 |
Pending
|
Diagnostics |
Urinary Podocyte Excretion as a Diagnostic Marker for Preeclampsia
Preeclampsia is a pregnancy-specific disease characterized by hypertension and occurrence of protein in the ...
|
| 2007-103 |
Pending
|
Research Tools |
In Vitro and In Vivo Models of TDP-43 and TDP-43 as Biomarker for Neurodegenerative Diseases
The abnormal accumulation of TDP-43 protein has been recently identified as the major protein constituent for ...
|
| 2007-104 |
None
|
Research Tools |
Lrrk2 Antibodies (Revised 6-19-2007)
Human leucine-rich repeat kinase 2 (Lrrk2) antibodies, raised to sequence peptides in rabbits and used to ...
|
| 2007-106 |
None
|
Therapeutics |
Interaction of Alpha,Beta-dehydroalanine Containing Peptides with Amyloid-beta (Abeta) Peptides Involved in Alzheimer's Disease
The aggregates formed by a peptide called amyloid-beta(Abeta) in brain, are widely believed to be the main ...
|
| 2007-119 |
None
|
Research Tools |
TDP-43 Overexpressing Mice: A Transgenic Model of Dementia
TDP-43 is a major protein constituent of ubiquitin-positive inclusions in patients with dementia, including ...
|
| 2007-120 |
None
|
Research Tools |
mTau Overexpressing Mice: A Transgenic Model of Dementia
Accumulation of tau in neurofibrillary tangles is an important pathological indicator of several ...
|
| 2007-122 |
None
|
Medical Devices |
Dialysis Tubing Connection Improvement
We have developed a "clip" that will fit over the 3 most common dialysis machine-to-patient tubing sets. The ...
|
| 2007-134 |
None
|
Diagnostics |
Breast Cancer Risk Prediction Model
A multifeature model, based in our benign breast disease cohort, to predict risk of subsequent breast cancer. ...
|
| 2007-141 |
None
|
Medical Devices |
Intraoperative Surgical Warming Table
This invention is composed of a radiotranslucent frame with hollow tubework throughout that allows for the ...
|
| 2007-155 |
None
|
Research Tools |
Plasmodium Falciparum Signal Peptide Peptidase cDNA Plasmid Constructs
These are circular DNA plasmid constructs that encode for a gene called signal peptide peptidase. The gene ...
|
| 2007-156 |
None
|
Medical Devices |
J Hook
This invention organizes IV bags with a series of 7 hooks placed along a single 24" plastic hanger which ...
|
| 2007-166 |
None
|
Research Tools |
Detection of Cytochrome P450 (CYP) 2D7-CYP2D6 Recombinant Genes
This invention describes a method that allows for the detection of the CYP2D7-CYP2D6 recombinant gene. This ...
|
| 2007-172 |
Pending
|
Research Tools |
Method for Estimating Diversity of Receptors Expressed by Thymus-Derived Lymphocytes
Thymus-derived (T) lymphocytes are important for controlling infections and cancer. The ability to carry out ...
|
| 2007-175 |
None
|
Medical Devices |
Pressure Ulcer Prevention Bed
Inspired by the contoured shape of a satellite dish, the Pressure Ulcer Prevention bed matches the natural ...
|
| 2007-177 |
None
|
Diagnostics |
Automated Vortexing Sonicator for Dislodging Bacteria from Biofilms
An interdisiplinary group at Mayo Clinic has demonstrated a procedure for sampling the bacteria resident in ...
|
| 2007-187 |
Pending
|
Therapeutics |
CD38 as a Target for Obesity, Metabolic Syndrome Related Disorders, and Dementia (Including Alzheimer's Disease)
Obesity is one of the major health problems of our times. Elucidating the signaling mechanisms by which high ...
|
| 2007-219 |
Pending
|
Diagnostics |
A Clinical Test for the Identification of Amyloid Proteins in Fat Aspirate Biopsy Specimens by Mass Spectrometry
The management of systemic amyloidosis relies on the treatment of the underlying etiology and differs ...
|
| 2007-229 |
Pending
|
Diagnostics |
Quantitation of Lobular Involution for Breast Cancer Risk Prediction
Our group was the first to describe that the process of age-related involution (or regression) of the ...
|
| 2007-230 |
None
|
Research Tools |
Human IAPP Knock-In Mouse
We have replace the mouse islet amyloid polypeptide (IAPP, amylin) gene with the human IAPP gene. Human IAPP ...
|
| 2007-235 |
None
|
Research Tools |
Cell Line Established from Ileal and Rectal Carcinoid Tumors
Carcinoids of the intestine are the most common gastrointestinal carcinoid tumors. Therapeutic options to ...
|
| 2007-240 |
None
|
Research Tools |
Dominant Negative SINA/SIAH Cell Lines and Transgenic Mouse Lines
A number of stable human pancreatic cancer cell lines (MiaPaCa and Panc-1) have been generated that expressed ...
|
| 2007-244 |
None
|
Research Tools |
Monoclonal Antibody PR11
PR11 is a mouse monoclonal antibody against the progesterone receptor protein. It binds specifically to ...
|
| 2007-246 |
None
|
Research Tools |
Monoclonal Antibody 4F3
4F3 is a mouse monoclonal anitbody against the protein Hsp90. It binds specifically to Hsp 90 from avian ...
|
| 2007-258 |
None
|
Research Tools |
Antibody to GALC
Monoclonal antibodies to GALC for use for disease research and as a histological lysosomal marker. ...
|
| 2007-259 |
None
|
Research Tools |
Generation of EBV-Transformed B-Cell Lines from CVID Patients with TACI Mutation
We have generated 2 B-cell lines from 2 individual CVID patients who have a specific mutation in the TACI ...
|
| 2007-288 |
None
|
Research Tools |
LRRK2 Knock Out Mice
Mice in which the endogenous leucine-rich repeat kinase 2 gene (LRRK2) has been ablated. Exon 41 has been ...
|
| 2007-294 |
Pending
|
Therapeutics |
Small-Molecule Inhibitors of Ricin
Seeds from the castor bean plant, Ricinus communis, are poisonous to humans, animals, and insects. One of the ...
|
| 2007-300 |
None
|
Research Tools |
Recombinant Mature Form of Human Frataxin Protein
Friedreich ataxia (FRDA) is an autosomal recessive degenerative disease caused by a deficiency of frataxin, a ...
|
| 2007-323 |
None
|
Research Tools |
AbS1 a Monoclonal Antibody to GCUNC45
This is a monoclonal antibody against GCUNC45 (General Cell UNC45) also called SMAP-1 which has sequence ...
|
| 2007-324 |
None
|
Research Tools |
Monoclonal Antibody to tsp23 (transcript like p23)
This is a monoclonal antibody, produced in mice, to the human protein tsp23 which has sequence similarity to ...
|
| 2007-327 |
None
|
Research Tools |
High-Throughput Cell-Based Assay for Lrrk2 Activity
Leucine-rich repeat kinase 2 (lrrk2) exits as a dimer, and with associated proteins probably forms a higher ...
|
| 2007-330 |
None
|
Research Tools |
iLRRK2 Wild-Type and Mutant (G2019S) Transgenic Mice
We created mice that contain human LRRK2 cDNA encoding either the wild-type or G2019S mutant form of the gene ...
|
| 2006-024 |
Pending
|
Therapeutics |
Immunogenic Epitopes of the Human Folate Receptor Alpha
Breast and ovarian cancers overexpress the folate receptor alpha. We identified several epitopes to which ...
|
| 2006-042 |
Pending
|
Research Tools |
A System for Monitoring Ligand-dependent and Ligand-independent Androgen Receptor Activity
The androgen receptor is a protein that mediates androgen signaling in the body. In prostate cells, for ...
|
| 2006-055 |
None
|
Research Tools |
Human Breast Cancer Cell Lines
We have developed unique breast cancer cell lines with inducible estrogen receptor isoforms (alpha and beta) ...
|
| 2006-059 |
None
|
Research Tools |
Antibodies Toward Intracellular Signaling Molecules: WAVE2, Ev1, VASP, HS1, STIM, CIN85 and TUBA
Peptide or GST-fusion proteins containing antigenic epitopes of WAVE2, Evl, VASP, HS1, STIM, CIN85 and TUBA ...
|
| 2006-060 |
Pending
|
Therapeutics |
New Source for Research and Therapeutic Cells from Apheresis Waste Products of Normal Donors
This invention describes a new source of cells for therapeutic and research use obtained as a by-product of ...
|
| 2006-067 |
Pending
|
Diagnostics |
A t(1;19)(q10;p10) Mediates the Combined Deletions of 1p and 19q in Human Oligodendrogliomas and Predicts and Better Prognosis of These Patients
Combined deletions of the chromosomes 1p and 19q arms are associated with glioma of oligodendroglial lineage. ...
|
| 2006-073 |
None
|
Software |
CITES: Cosmology Inspired Tissue Engineering Scaffolds
We disclose a method which mimics the primordial processes which initiated the morphogenesis of the now ...
|
| 2006-079 |
Pending
|
Therapeutics |
Tranvesical Peritoneoscopy and Retroperitoneoscopy: The Urinary Tract as a Portal for Natural Orfice Surgery
A new approach to minimally invasive surgery involving access to the peritoneal cavity and retroperitoneum ...
|
| 2006-086 |
Pending
|
Therapeutics |
Programming the Polarity of the Immune Response in an Anitgen Independent Fashion
The acquired immune response is focused on specific antigens. Typically these antigens are discrete entities ...
|
| 2006-090 |
None
|
Medical Devices |
Myers Specialty Instrument Package (Includes Clamp, Forceps, & Scissors)
The Myers Specialty Instrument Package, developed for erectile function-preserving neurovascular bundle ...
|
| 2006-100 |
None
|
Research Tools |
Assays for Detection of Malarial Signal Peptide Peptidase (SPP) Activity and Use in Identifying Novel Anti-Malarial Drugs
We have identified and synthesized a gene encoding a novel drug target in the malarial parasite (Plasmodium ...
|
| 2006-104 |
Pending
|
Diagnostics |
Soluble Prostate Diagnostic/Early Detection Biomarkers
Mayo Clinic researchers have identified seventy genes encoding proteins with putative diagnostic value for ...
|
| 2006-115 |
Pending
|
Diagnostics |
Pan Anti-beta Amyloid scFVs, Anti-beta Amyloid scFVs Specific for Abeta-40 and Abeta-42 and Methods for Their Delivery to Treat or Prevent Alzheimer's Disease
Accumulation of Abeta in the brain of patients who suffer from Alzheimer?s disease (AD) triggers a complex ...
|
| 2006-130 |
Pending
|
Diagnostics |
Role of Progranulin in Neurodegenerative Disease
Frontotemporal dementia (FTD) is the second most common cause of dementia in people under 65 years. A large ...
|
| 2006-137 |
Pending
|
Software |
A Novel Systems Biology Approach to Identify Subtle Disease Including Prediabetes Mellitus
A method has been developed for assessing an inter-dependent biological system wherein said methods comprise ...
|
| 2006-149 |
Pending
|
Diagnostics |
Molecular Markers for Biological Response to PPARgamma Agonists
Peroxisomal proliferating activated receptor (PPARgamma) agonists are ligands that bind to PPARgamma, a ...
|
| 2006-157 |
Pending
|
Therapeutics |
Superparamagnetic Cobalamin Analogs for the In Vitro and In Vivo Isolation, Localization and Destruction of Malignant Cells
A superparamagnetic nanoparticle of iron oxide is covalently bonded to Vitamin B12. The B-12-Iron oxide ...
|
| 2006-159 |
Pending
|
Therapeutics |
ABC-NP - - An Aquaretic and Natriuretic Peptide Without Vasodilatory Properties
The Natriuretic peptides (NP) are a naturally occurring family of peptides that increase salt excretion in ...
|
| 2006-161 |
Pending
|
Diagnostics |
Gene Can Predict Aggressiveness of Prostate Cancer
A set of prognostics markers for PCa has been identified using novel bioinformatics algorithms which analyze ...
|
| 2006-162 |
Pending
|
Diagnostics |
Proliferation (Cell Cycle) Related Genes Can Predict Aggressiveness of Prostate Cancer
A set of prognostics markers for PCa has been identified using novel bioinformatics algorithms which analyze ...
|
| 2006-179 |
Pending
|
Diagnostics |
Predictive Biomarkers for Parkinson's Disease
We explored an available whole-genome association dataset to identify single nucleotide polymorphisms within ...
|
| 2006-189 |
Pending
|
Diagnostics |
Markers That Can Predict Aggressiveness of Prostate Cancer
A set of prognostics markers for PCa has been identified using novel bioinformatics algorithms which analyze ...
|
| 2006-191 |
Pending
|
Medical Devices |
Cement Heat Management Device
This device is designed to extract heat during cement polymerization. The device consists of any ...
|
| 2006-194 |
Pending
|
Therapeutics |
Genetic Polymorphisms in the Human Serotonin Transporter (SLC6A4) Gene in Caucasian, African American, Han Chinese, and Mexican American Populations (Revised June 2007)
The SLC6A4 gene (also referred to as HTT, 5HTT, OCD1, SERT, 5-HTT, and hSERT) encodes an integral membrane ...
|
| 2006-202 |
Pending
|
Diagnostics |
Novel Cytochrome P450 (CYP) 2D6 Gene and CYP2D7 Pseudogene Arrangement and Tests for Detection of These Newly Discovered Gene Arrangements
The CYP2D6 gene makes a protein that metabolizes drugs. This gene is highly variable. It can have different ...
|
| 2006-231 |
None
|
Research Tools |
Polyclonal Antibodies to the CRAC Regulators Orail and STIM1
Rabbit polyclonal antibodies were generated to two components of the calcium-release activated calcium (CRAC) ...
|
| 2006-236 |
Pending
|
Medical Devices |
Posterior Lamellar Keratoplasty Graft Deployment Device: Mayo Ophthalmology
A posterior lamellar keratoplasty graft deployment device has been designed and is currently being tested. ...
|
| 2006-241 |
Pending
|
Therapeutics |
Anti-Amyloid scFVs and Methods for Their Delivery to Treat or Prevent Alzheimer's Disease
Numerous pathological conditions including Alzheimer's Disease (AD) are associated with the deposition of ...
|
| 2006-243 |
None
|
Therapeutics |
Mayo Clinic Nicotine Depedence Education Program: Customized Workshops for Health-Care Professionals
A training program to teach health-care professionals how to effectively treat patients who use tobacco. The ...
|
| 2006-244 |
None
|
Therapeutics |
Your Path to Smokeless Tobacco Freedom Patient Manual, Facilitator's Guide, Illustrations, and DVD
Your Path to Smokeless Tobacco Freedom (Your Path) MC6013-01, is a new intervention booklet for patients who ...
|
| 2006-255 |
Pending
|
Diagnostics |
Cofilin-1
A novel plasma biomarker for human heart failure....
|
| 2006-260 |
Pending
|
Software |
Algorithm for Identification of Regions of Change in Three Dimensional Magnetic Resonance Brain Images
The algorithm examines serial three dimensional magnetic resonance brain image data and identifies regions ...
|
| 2006-290 |
Pending
|
Diagnostics |
B7-H3 as a Marker and Target for Cancer Diagnosis, Prognostication, Tumor Vasculature and Therapy
B7-H3 is expressed by kidney and prostate cancer and in these cancers is predictive of cancer progression and ...
|
| 2005-003 |
Pending
|
Therapeutics |
Use of SDF-1 and other CXCR4 Agonists to Antagonize TLR4
Toll-like receptor 4 (TLR4) transmits signals to various cells and in so doing can cause inflammation, the ...
|
| 2005-008 |
Pending
|
Electronic Devices |
Automatic Energy-Efficient Bathroom Exhaust Fan Control
The proposed invention turns on the bathroom exhaust fan automatically when someone takes a shower. A ...
|
| 2005-014 |
None
|
Research Tools |
Purified Rho Family GTP-binding Proteins
Proteins of the Rho family of GTP-binding proteins regulate multiple cellular phenomenon. There are 17 ...
|
| 2005-016 |
Pending
|
Research Tools |
rTg4510 Mouse Model of Tauopathy
These transgenic mice have regulatable tau expression and profound neurofibrillary pathology, ...
|
| 2005-017 |
Pending
|
Diagnostics |
Tandem Mass Spectrometry (MS/MS) of Thiopurine Methyltransferase (TPMT) Reaction Products in order to Quantitate TPMT Enzyme Activity
This invention provides methods and materials related to the measurement of TPMT enzymatic activity in ...
|
| 2005-022 |
Pending
|
Software |
Electronic Stool Subtraction Algorithm for CT Colonography Without Bowel Preparation
CT colonography (CTC) offers advantages for colon examinations such as lower risk and less patient ...
|
| 2005-023 |
None
|
Software |
Intraoperative 3D Seed Localization and Dose Analysis in Prostate Brachytherapy
A synergistic integration of two novel algorithmic procedures into a software program for accurate, rapid 3D ...
|
| 2005-026 |
Pending
|
Electronic Devices |
Self-Contained Semi-Active Cooling Mechanism for Very High Power Density Integrated Circuits and Electronic Modules Using a Reversible Endothermic Chemical Reaction
This invention is a completely self-contained and encapsulated "package" into which a high power integrated ...
|
| 2005-044 |
Pending
|
Medical Devices |
Saphenous Vein Clipping and Injection System for Use in Duplex Guided Extraluminal Endoscopic Saphenofemoral Junction Clipping with Retrograde Foam Sclerotherapy
The proposed technology is a simpler and safer method for treating varicose veins of the lower extremities. ...
|
| 2005-048 |
Pending
|
Therapeutics |
Use of Chaetocin and Related Compounds as Cancer Therapeutics
Chaetocin, a previously identified fungal byproduct, was found to kill cancer cells at low nanomolar drug ...
|
| 2005-055 |
Pending
|
Medical Devices |
Anterior Adherent Thoracolumbar Spine Plate
This implant is a fixation device, shaped in the form of a plate for use in the fixation and stabilization of ...
|
| 2005-059 |
Pending
|
Diagnostics |
Genetic Test Predicting Brain Aneurysm Rupture
Mayo Clinic researchers have developed a novel genetic test that predicts the rupture of brain aneurysm. The ...
|
| 2005-072 |
Pending
|
Diagnostics |
Fluorescent In Situ Hybridization (FISH) Probe Development to Detect Immunoglobulin Light Chains Kapa (IGK) and Lambda (IGL) Translocations
Lymphoma, the cancer to the lymph glands and lymphocytes develop as a consequence of acquired ...
|
| 2005-088 |
None
|
Research Tools |
Quality Control Measures for Genotyping Polymorphic Genes
Polymorphic genes pose problems for genotyping measurements when PCR amplification is involved. Mutations ...
|
| 2005-104 |
None
|
Research Tools |
Stealth and Targeted Envelope for Vector Delivery
Several human viruses are being developed as novel agents for the treatment of human cancer even if ...
|
| 2005-107 |
None
|
Research Tools |
Stably Transfected Cell Lines Expressing APPwt or Alkaline Phosphatase-APP105 Fusion that Produce Extremely High Levels of Abeta42
These cell lines express a protein (APP) that is cleaved to form the Amyloid beta protein (Abeta) deposited ...
|
| 2005-108 |
Pending
|
Therapeutics |
Non-Abeta Based Amyloid Vaccines: Alternative Strategies to Promote Generic Anti-Amyloid Responses to Treat Alzheimer's Disease and Other Human Amyloidoses
Amyloid deposition is a process whereby a protein abnormally folds into an insoluble form. Various human ...
|
| 2005-112 |
None
|
Therapeutics |
My Path to a Smoke-Free Future - An Interactive Patient Manual
An interactive patient manual to assist the health care provider in delivering an effective intervention to ...
|
| 2005-115 |
None
|
Medical Devices |
Device for Intracorporeal Vascular Exit and Reentry
Frequently in medical practice there is a need for devices to access tissues that may be difficult to reach. ...
|
| 2005-123 |
Pending
|
Therapeutics |
RHIGM12 Recombinant Antibody
This invention relates to an antibody that can bind to and cross-link B7-DC polybeptides on the surface of a ...
|
| 2005-124 |
Pending
|
Diagnostics |
Functionally Relevant, Common Mutations in the Human Sulfotransferase 1A1 (SULT 1A1) Gene
Common, functionally relevant mutations in the SULT1A1 have been recently discovered. These mutations have a ...
|
| 2005-127 |
None
|
Research Tools |
Antibodies to Isoforms of HP-1 and SP-1
Antibodies to various isoforms of HP-1 and SP-1.
...
|
| 2005-131 |
None
|
Therapeutics |
Facilitator's Guide and DVD for
A guide for the use of the patient intervention manual: "My Path to a Smoke Free Future". It contains ...
|
| 2005-136 |
Pending
|
Medical Devices |
Semi-constrained 1st Carpometacarpal Implant Arthroplasty
This device is used to treat a painful thumb base joint (1st CMC joint) from arthritis. It is composed of ...
|
| 2005-141 |
Pending
|
Therapeutics |
Combination of Phosphodiesterase V Inhibition and Natriuretic Peptides for the Treatment of Cardiovascular and Renal Diseases
Combination of 2 types of drugs, phosphodiesterase V inhibitors and natriuretic peptides, to treat heart and ...
|
| 2005-143 |
Pending
|
Medical Devices |
Phased Array Designed for Torso Imaging
4/8 channel phased array coil designed for abdominal imaging....
|
| 2005-144 |
Pending
|
Medical Devices |
Phased Array Designed for Brachial Plexus Nerve Imaging at 1.5 or 3T MRI
4/8 or more channel array designed to image left, right, or bilateral brachial plexus nerves at 1.5T or 3T....
|
| 2005-145 |
Pending
|
Medical Devices |
Phased Array Receive Only Coil Designed for Leg Imaging
4/8 or more channel receive only array designed for long bone imaging at 1.5 or 3T....
|
| 2005-146 |
Pending
|
Medical Devices |
Hand Phased Array Coil
4 or 8 channel receive only phased array coil used for hand imaging in MRI at 1.5T and 3T
...
|
| 2005-147 |
Pending
|
Medical Devices |
Phased Array Receiver Coil Designed for Arm Imaging
4/8 or more channel receive only array designed for arm, elbow, extremity imaging
...
|
| 2005-156 |
Pending
|
Diagnostics |
Genetic Polymorphisms in the Human Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) gene in Caucasian, African American, Han Chinese and Mexican American Populations
Some of the known substrates of CYP19A1 (aromatase) include testosterone and androstenedione. It is expressed ...
|
| 2005-165 |
Pending
|
Therapeutics |
Protease Inhibitors as Immune Adjuvants
The use of HIV protease inhibitors in HIV negative patients increases naive T cell production, which may be ...
|
| 2005-172 |
Pending
|
Therapeutics |
Small-Molecule Antidotes to Botulinum Neurotoxins Serotype A
Serotype selective and nonpeptidic inhibitors of botulinum neurotoxin serotype A (BoNTA) have been developed. ...
|
| 2005-174 |
None
|
Diagnostics |
Major Basic Protein Homolog (MBP2): A Specific Human Eosinophil Marker
Eosinophils are blood leukocytes that are characteristically associated with allergic reactions. For example, ...
|
| 2005-178 |
Pending
|
Diagnostics |
Identification of Naturally Processed and Presented Vaccinia Peptides
We have successfully identified a naturally processed and presented vaccinia peptide from a class 1 HLA ...
|
| 2005-183 |
Pending
|
Medical Devices |
Temporomandibular Joint Fossa-Eminence Metal Prosthesis
A metal onlay implant surgically placed in the temporomandibular joint fossa/eminence (temporal bone) ...
|
| 2005-192 |
Pending
|
Medical Devices |
A Device for Tracking Fetal Heart Rate During Fetal Monitoring
Assessment of fetal well-being requires a continuous signal from the fetal heart to assess beat-to-beat and ...
|
| 2005-204 |
Pending
|
Research Tools |
Analytical Reconstruction of Unobserved Ensemble Signals in Biomedical Systems
The invention is a network of coupled equations with deterministic and stochastic features designed to ...
|
| 2005-210 |
Pending
|
Therapeutics |
Endogenous Agonist Mechanism of Action of Class B GPCRs, Key to Small Molecule Drug Development
We have identified a novel molecular mechanism of action of Class B GPCRs, a family that includes important ...
|
| 2005-211 |
Pending
|
Diagnostics |
Discovery of a Novel Spliceoform of the Secretin Receptor
Mayo Clinic researchers identified a novel abnormal spliceoform of the secretin receptor in pancreatic and ...
|
| 2005-215 |
Pending
|
Therapeutics |
Long Acting Atrial Natriuretic Peptide (LA-ANP)
LA-ANP is a novel Mayo developed peptide with potential use as a therapeutic agent in the treatment of heart ...
|
| 2005-229 |
Pending
|
Medical Devices |
Micro-minimally Invasive Surgery (MMIS) Instrumentation for Ultrasound Guided Surgery
This instrumentation represents platform technology utilized to perform ultrasound guided minimally invasive ...
|
| 2005-231 |
None
|
Research Tools |
Prostate Marker Validation Database
Under the Minnesota Partnership, researchers at the University of Minnesota and at Mayo have developed a ...
|
| 2005-246 |
None
|
Electronic Devices |
Pressure Mapping Seat Cover with Alarm and Data Tracking System for Wheelchair Users
The X-Sensor pressure mapping system (www.xsensor.com) has the capability of measuring pressures on the skin ...
|
| 2005-247 |
None
|
Research Tools |
MAPT (tau) cDNA Clones in pCDNA 3.1
MAPT (tau) is a protein involved in regulating the structure and function of nerve cells. The clones contain ...
|
| 2005-255 |
None
|
Research Tools |
pCT26, pFP93, pCT26sin
FIV vector components: transfer vectors (pCT26, pCT26sin) and packaging constructe (pFP93).
...
|
| 2005-277 |
None
|
Therapeutics |
Administration of Low Doses of Natriuretic Peptides to Improve Left Ventricular Remodeling after Myocardial Infarction
After a heart attack, the heart tries to repair itself and undergoes changes in its shape, structure and ...
|
| 2005-287 |
Pending
|
Medical Devices |
A Non-Invasive 24-Hour Intraocular Pressure Monitor
This device is designed to monitor intraocular (eye) pressure over a 24 to 48 hour period, awake and asleep, ...
|
| 2005-297 |
None
|
Therapeutics |
Targeting p120 Catenin Function to Block Tumor Growth and Metastasis
p120 catenin is a protein involved in holding cells together by promoting cell-cell adhesion. However, in ...
|
| 2005-305 |
Pending
|
Diagnostics |
Assessing Outcomes for Breast Cancer Patients Treated with Tamoxifen
In the adjuvant treatment of estrogen receptor (ER) positive breast cancer, hormonal therapy reduces the risk ...
|
| 2005-315 |
Pending
|
Diagnostics |
Measurement of Circulating DHEA Levels for the Determination of Histological Severity of Non-alcoholic Fatty Liver Disease
The severity of non-alcoholic fatty liver disease (NAFLD) can be determined with a high degree of accuracy ...
|
| 2005-316 |
None
|
Research Tools |
Ly9 (CD229) Knock Out Mice
These mice do not express the gene for CD229.
...
|
| 2004-002 |
None
|
Medical Devices |
Suture-Mediated Closure Devices
This device serves to close body cavities deep to the skin surface through suture closure. The device can be ...
|
| 2004-004 |
Pending
|
Therapeutics |
Utility of PLVAP for Early Detection, Prognostic Prediction and Therapy of Liver and Other Cancers
Mayo Clinic researchers have produced antibodies against the protein product of a gene that is overexpressed ...
|
| 2004-011 |
Pending
|
Therapeutics |
Discovery and Identification of Naturally Processed and Presented HLA Class II Measles Vaccine Virus Peptides
Two measles vaccine virus-derived peptides, from the nucleoprotein (N peptide) and Phosphoprotein P peptide). ...
|
| 2004-012 |
Pending
|
Electronic Devices |
Differential Signal Termination and Sampling Blocks
There are a variety of devices being developed to significantly improve the testing, characterization, and ...
|
| 2004-017 |
Pending
|
Medical Devices |
CT Bellows System
Bellows and patient feedback system for use in CT....
|
| 2004-020 |
None
|
Software |
Interactive and Efficient Cell Counter and Analyzer Program (C-CAP)
The CCAP program accurately and efficiently counts and analyzes cells in microscope images. A user ...
|
| 2004-022 |
None
|
Research Tools |
Genetically Modified Mice Susceptible to Pathogens Infection
Mice expressing human CD46 with human-like tissue specificity and efficiency. For additional information, ...
|
| 2004-023 |
|
Software |
Prior Knowledge-Based Rapid Predicted Preview of Multiple Contract Magnetic Resonance Images Derived from a Single Time Budgeted Acquisition
This invention presents a method for producing multiple MR images with different contrast from a single image ...
|
| 2004-027 |
Pending
|
Software |
Techniques to Rate the Validity of Multiple Methods to Process Multi-dimensional Data
To accomplish a given computational task, a number of algorithmic and heuristic approaches can be implemented ...
|
| 2004-055 |
None
|
Software |
Robust Fast Automatic and Parameter Free Skull Stripping of MRI T2-Data
This invention performs a robust, fast and fully automatic parameterization of T2 images into an intensity ...
|
| 2004-056 |
None
|
Software |
High Resolution Three Dimensional Talairach Labels for Human Brain Mapping
This disclosure provides a way to improve the Talairach Labeling scheme that allows labelings to be reported ...
|
| 2004-061 |
None
|
Research Tools |
Polyclonal Antibodies Specific for SRC-2 and REA Steroid Receptor Coregulators
We have developed a series of polyclonal antibodies specific for SRC-2 and REA steroid receptor coregulators. ...
|
| 2004-062 |
None
|
Research Tools |
Osteoblast with Estrogen Receptor Isoform Homodimers and Heterodimers (alpha & beta)
We have developed osteosarcoma cell lines (U2OS) which express both the ER-alpha and ER-beta isoforms and ...
|
| 2004-068 |
Pending
|
Therapeutics |
Methods and Materials for Treating Digestive Motility Disorders
Methods and materials have been disclosed to increase the number of ICC (interstitial cells of Cajal) within ...
|
| 2004-084 |
Pending
|
Software |
A Method for Repeated, Rapid Fabrication of Enhanced, Porous, Tissue Engineered Scaffolds
Tissue engineering attempts to address the widening gap between the demand and supply of organ and tissue ...
|
| 2004-085 |
Pending
|
Software |
Space Optimal Unit Cell Based Tissue Engineering Scaffolds
Tissue engineering scaffolds are biomimetic "trellis-like" structures which, on implantation and integration, ...
|
| 2004-105 |
Pending
|
Medical Devices |
Detection of Blood Flow Using Emitted Light Absorption
This invention is related to detection of blood pressure, blood flow and heart rhythm abnormalities ...
|
| 2004-108 |
None
|
Research Tools |
51KO Mouse Line
The invention is a mouse line in which we disrupted the gene for FKBP51, a protein component of steroid ...
|
| 2004-109 |
None
|
Research Tools |
52KO Mouse Line
This invention is a mouse line in which we disrupted the gene for FKBP52, a protein component of steroid ...
|
| 2004-133 |
None
|
Research Tools |
Advanced FIV Vector System
A highly engineered FIV vector system useful for delivering genes to cells....
|
| 2004-139 |
Pending
|
Diagnostics |
In vivo Visualization of Alzheimer's Amyloid Plaques without a Contrast Agent
One of the cardinal pathologic features of Alzheimer's disease (AD) is formation of senile or amyloid, ...
|
| 2004-146 |
None
|
Software |
Stand Alone Software Module for Segementation and Modeling of Cardiac Chambers from 3D Volumetric Images
This software program will run on an open platform PC-based system and with minimal user guidance will ...
|
| 2004-152 |
Pending
|
Therapeutics |
Method of Preventing the Formation of Antibodies in Patients Undergoing Successive Treatments with Therapeutic Antibodies
This invention consists of methods and materials for reducing a mammal?s ability to produce antibodies ...
|
| 2004-153 |
Pending
|
Diagnostics |
Detection of Circulating Tumor Cells Carrying the BRAF V599E Mutation
A proportion of human cancers, regardless of type, contain a somatic mutation in the BRAF gene, which changes ...
|
| 2004-154 |
None
|
Research Tools |
GALV.fus Gene
Expression of GALV-fuse gene in tumor cells causes them to fuse with their nontransfected neighbors forming a ...
|
| 2004-158 |
Pending
|
Research Tools |
Transgenic Mouse Model of HCV Infection
Mayo Clinic Researchers have developed a novel transgenic mouse that contains transplanted human hepatocytes ...
|
| 2004-159 |
Pending
|
Diagnostics |
Use of Beta Atrial Natriuretic Peptide as a Screening Biomarker for the Detection of Systolic Left Ventricular Dysfunction and as a Co-Marker with BNP to Detect and Evaluate Heart Failure
The heart releases a peptide called atrial natriuretic peptide (ANP). In heart failure, an abnormal form of ...
|
| 2004-162 |
None
|
Diagnostics |
GLTSCR1 Gene Analysis for Prostate Cancer
Identification of GLTSCR1 gene mutations to predict susceptibility to prostate cancer and to preduct prostate ...
|
| 2004-176 |
Pending
|
Diagnostics |
Plasma ABeta42/ABeta40 Ratio is a Good Predictor of Alzheimer's Disease
Patients with Alzheimers Disease have large numbers of senile plaques in their brains. A relatively rare ...
|
| 2004-181 |
Pending
|
Research Tools |
Method of Demonstrating the Presence of Fungi in Human Body Fluids
A research tool/method to detect the presence of fungal organisms in human body fluids, particularly from ...
|
| 2004-185 |
Pending
|
Diagnostics |
Identification of Mutations in PARK8, a Locus for Familial Parkinson's Disease
Discovery of the genetic cause of clinical, late-onset (typical) Parkinson's disease in multiple families ...
|
| 2004-199 |
None
|
Diagnostics |
Using Resonance of Artery for Estimation of Arterial Elastic Modulus
It has long been recognized that a high percentage of all cardiovascular disease is associated with a ...
|
| 2004-224 |
Pending
|
Therapeutics |
Novel Anti-SARS Drugs: Small-Molecule Inhibitors of SARS Chymotrypsin-Like Cysteine Proteinase
Through in silico screening and NMR spectroscopic studies, we have discovered a group of drug-like molecules ...
|
| 2004-225 |
Pending
|
Diagnostics |
Prognostic and Diagnostic Tests for Clear Cell Renal Carcinoma
Gene Expression profiling was used to identify a set of genes that are associated with the progression of ...
|
| 2004-231 |
Pending
|
Electronic Devices |
Efficient Digital Synthesis of Waveforms Based on Periodic Functions
The present invention details a substantial implementation improvement for a broad class of Direct Digital ...
|
| 2004-235 |
Pending
|
Electronic Devices |
High Speed Clock Duty Cycle Correction and Adjustment Circuit
The fully differential circuit in a SiGe BiCMOS process accepts an input clock with duty cycle error and ...
|
| 2004-237 |
Pending
|
Software |
Detection of Shear Waves Using Pulse Echo Ultrasound with Kalman Filtering
The present invention detects the harmonic motion of vibro-acoustography using pulse echo ultrasound and ...
|
| 2004-244 |
Pending
|
Diagnostics |
Measuring Vitamin D2 and D3 using online extraction and Liquid Chromatography Tandem Mass Spectrometry
Deuterated stable isotope (d3-25-hydroxyvitamin D) is added to a 0.2-mL plasma sample as internal standard. ...
|
| 2004-245 |
Pending
|
Electronic Devices |
Multi-beam Radiation Force Generator for Selective Excitation of Vibrational Modes in Objects
The method developed allows selective excitation of an object using the interference of sonic beams. As an ...
|
| 2004-247 |
None
|
Software |
Adaptive Piece-wise Registration for Automated Fusion of Point Cloud Coordinates and Anatomic Volume Images
We have developed a robust, automated point-cloud to surface registration using piece-wise adaptive matching ...
|
| 2004-252 |
Pending
|
Medical Devices |
Fallopian Tube Ostia Location and Marking Device
Device that uses methylene blue to mark tubal ostia enabling location of fallopian tube ostia after ...
|
| 2004-268 |
Pending
|
Undetermined |
Somatostatin Analogs as Potential Therapeutic Treatment of Hepatic Polycystic Disease
Preclinical data suggests that somatostatin analogs may be useful in treating PKD....
|
| 2004-271 |
None
|
Software |
3D Image Processing for Whole-Bone Integrity Measurement and Analysis
The Biomedical Imaging Resource working with the Endocrine Research Unit has developed a unique and powerful ...
|
| 2004-273 |
|
Diagnostics |
Human Glutathione S-transferase Omega 2 (GSTO2) Genetic Polymorphisms
GST02 is a phase II enzyme that utilize glutathione in reactions contributing to the transformation of a wide ...
|
| 2004-274 |
None
|
Diagnostics |
Human Hydroxy-delta-5-steroid dehydrogenase, 3 beta-and steroid delta-isomerase 1 (HSD3 B1) Genetic Polymorphisms
Substrates include pregnenolone, 17-hydroxypregnenolone (17-OH-Preg), dehydroepiandrosterone (DHEA) and ...
|
| 2004-276 |
None
|
Medical Devices |
Hand-held Vaginal Retractor
A hand-held retractor that is placed in the vagina during surgery to repair vaginal vault prolapse following ...
|
| 2004-284 |
Pending
|
Therapeutics |
Inhibitors of Excision Repair as a Therapeutic to Prevent DNA Amplification Events
We have found that onset of neuronal toxicity in HD (Huntington's) may arise from cellular expansion of ...
|
| 2004-286 |
Pending
|
Electronic Devices |
Packaging for High Power Integrated Circuits Using Supercritical Fluid
This invention is a completely self-contained and encapsulated "package" into which a high power integrated ...
|
| 2004-290 |
Pending
|
Electronic Devices |
A Remote System for Monitoring Core Temperature
This disclosure describes a system to monitor body core temperature in situations where individuals may ...
|
| 2004-291 |
Pending
|
Research Tools |
Identification of a Novel LRRK2 Mutation, 6055G>A (G2019S), Linked to Autosomal Dominant Parkinsonism in Families from Several European Populations
Autosomal dominant parkinsonism linked to chromosome 12q12 (PARK8) has recently been attributed to pathogenic ...
|
| 2004-305 |
Pending
|
Therapeutics |
Preparation of Nanogold-VEGF Antibody Bioconjugates for Potential Anti-Angiogenic Therapy
In this invention we have prepared a number of nanobioconjugates comprising of gold nanoparticles and VEGF ...
|
| 2004-306 |
None
|
Therapeutics |
Preparation of Gold Nano Bioconjugates Comprising of Anticancer Drugs and Antiangiogenic Agent
(Patents logged on 05-019) In this invention we have prepared a number of nanobioconjugates comprising of ...
|
| 2003-008 |
Pending
|
Diagnostics |
-258 Parkin Promoter SNP
A -258 T/G polymorphism in the parkin gene promoter that is genetically associated with late-onset (typical) ...
|
| 2003-023 |
None
|
Research Tools |
Apparatus and Means to Measure Vessel Stiffness
Ultrasonic radiation pressure is used to induce surface waves in the wall of a vessel. The speed and ...
|
| 2003-028 |
Pending
|
Medical Devices |
Wire-less MRI Coils
This invention uses optical or RF means to transfer the MRI coil signal from the coil to the scanner reciever ...
|
| 2003-032 |
Pending
|
Therapeutics |
Prevention and Intervention in Allergic Asthma Using B7-DC Cross-linking Antibody
Mayo Clinic researchers have developed a human monoclonal antibody that crosslinks the B7-DC receptor on ...
|
| 2003-034 |
Pending
|
Medical Devices |
Lucent Uniform Compression Inflatable Dressing
Device controls tissue swelling subsequent to trauma or surgery; applies uniform pressure; permits visual ...
|
| 2003-047 |
|
Research Tools |
Mouse Model of Glucose Intolerance and Role of Myosin Heavy Chain in Glucose Intolerance
Mayo Clinic researchers have developed a novel transgenic mouse model that exhibits symptoms of glucose ...
|
| 2003-086 |
|
Medical Devices |
Sleep Support Belt for Individuals with Poor Sleep Hygiene Related to Obstructive Sleep Apnea and/or Snoring
A supportive device that facilitates proper sleep position in individuals with obstructive sleep apnea and/or ...
|
| 2003-088 |
Pending
|
Diagnostics |
Molecular Markers for Prostate Cancer
Molecular markers identified by DNA microarrays useful for diagnosis and prognosis of prostate cancer.
...
|
| 2003-089 |
Pending
|
Therapeutics |
Complexed Peptide and Adjuvant for Improved Vaccines
We have shown that peptides presented by major histocompatibility complex (MHC) class I molecules can be ...
|
| 2003-108 |
|
Research Tools |
Unique Phenotype of TIEG Knockout Mice
We have developed mice which contain a disruption in a nucleic acid encoding TIEG. The mice develop cardiac ...
|
| 2003-119 |
Pending
|
Medical Devices |
A Novel Lead Delivery Device
A device to facilitate epicardial placement of permanent pacing leads, ablation catheters, and other ...
|
| 2003-126 |
Pending
|
Medical Devices |
Radiolabeled Thymidine Solid-Phase Extraction Purification Method
This solid-phase extraction purification method can purify radiolabeled thymidine quickly and conveniently. ...
|
| 2003-134 |
Pending
|
Diagnostics |
Polymorphisms in GLTSCR1 Are Associated with Cancer Development
Deletions of chromosome regions in 1p and 19q have been associated with gliomas - especially ...
|
| 2003-138 |
None
|
Therapeutics |
In vivo Models to Study PPARgamma and Protein Kinase C Signaling in Colon Cancer
Transgenic mice expressing levels of PKCbetaII in the colonic epithelium can be used as a model to assess the ...
|
| 2003-149 |
|
Therapeutics |
Proteomic Design and Chemical Synthesis of Amino Acids with High Blood-Brain Barrier Permeability
The present invention is the protemic design and chemical synthesis of amino acid polymers with improved ...
|
| 2003-149 |
|
Diagnostics |
Proteomic Design and Chemical Synthesis of Amino Acids with High Blood-Brain Barrier Permeability
The present invention is the protemic design and chemical synthesis of amino acid polymers with improved ...
|
| 2003-150 |
|
Research Tools |
An IEX-1 Null Mutant Mouse
A mouse lacking both copies of the IEX-1 gene was generated. These mice have a mean arterial blood pressure ...
|
| 2003-157 |
None
|
Diagnostics |
Measurement of Superimposed P Wave Duration as a Quantitative Marker of Left Atrial Size
We describe a new method of ECG analysis which has the strongest quantitative correlation in comparison with ...
|
| 2003-185 |
Pending
|
Electronic Devices |
Modular Pipeline Fast Fourier Transform
The invention describes a new algorithm and hardware architecture to compute the fast Fourier transform ...
|
| 2003-190 |
Pending
|
Medical Devices |
Biofilm Removal From Surfaces
Vortexing sonication bath fluid prior to sonication significantly enhances the removal of bacterial biofilms ...
|
| 2003-196 |
Pending
|
Research Tools |
Transgenic Line of Mice Congenitally Devoid of Eosinophils
Transgenic mice were created through DNA microinjection of a construct utilizing mouse EPO derived regulatory ...
|
| 2003-199 |
Pending
|
Electronic Devices |
Ultra-Miniature Transceiver (Micro-miniature Transceiver, SOC, carried by a fly)
The invention is an ultra-miniature transceiver technology that allows positioning, data relaying and ...
|
| 2003-202 |
None
|
Medical Devices |
Scaphoid Fracture Highly Porous Metal Pin
Device combines stability of screw with ability to integrate with bone; can be used for bone fracture ...
|
| 2003-220 |
Pending
|
Therapeutics |
A Method to Reconstitute the T Lymphocyte Compartment
Mayo Clinic researchers are developing therapeutic strategies to reconstitute the T lymphocyte compartment.
...
|
| 2003-222 |
Pending
|
Research Tools |
Transgenic Mice Expressing Mutant Protein Kinase C lota in the Colonic Epithelium
These mice represent a model for colon cancer progression from adenoma to carcinoma. C57BI/6J mice were ...
|
| 2003-223 |
None
|
Diagnostics |
Genetic Variation in the CD25 Molecule Predisposes to Type 1 Diabetes
Discovery of single nucleotide polymorphisms in the CD25 molecule which increase susceptibility to type 1 ...
|
| 2002-001 |
Pending
|
Medical Devices |
Trans-Rectal Ultrasound (TRUS) Fiducial System for Minimally Invasive Image Guided Prostate Therapy
The device is a trans-rectal ultrasound (TRUS) probe holder which attaches to a transperineal template and is ...
|
| 2002-012 |
None
|
Medical Devices |
Sterile Intra-operative Arm Positioner for Shoulder Surgery
Currently looking for a licensing partner for arm positioner device for shoulder surgery that attaches to ...
|
| 2002-017 |
Pending
|
Therapeutics |
A Peptide Vaccine to Induce Immunity to Epstein Barr Virus
A promiscuous T cell peptide epitope from the EBNA2 antigen has been identified. T cells induced with this ...
|
| 2002-029 |
|
Diagnostics |
Computer-aided Detection of Liver Tumor Halos in Ultrasound Images
This invention developed a novel computer-aided method for identification of liver tumor halos. The edge of ...
|
| 2002-038 |
|
Medical Devices |
Synthetic Aortic Valve Leaflet With Inlaid Stress-Bearing Fibers and Synthetic Nodulus of Arantzius
A synthetic valve/leaflet for manufacturing cardiac valve prostheses - mechanical characteristics include ...
|
| 2002-039 |
|
Research Tools |
ICOS Mutants
This invention relates to T cell-mediate immune responses, and more particularly to compositions and methods ...
|
| 2002-062 |
None
|
Therapeutics |
Countermeasures to Anthrax
A group of chemical structures have been identified from in silico screening of a chemical database as ...
|
| 2002-066 |
Pending
|
Diagnostics |
Use of FISH Probes to Detect the t(4;14)(p16.3;q32) and t(14;16)(q32;q23) in Myeloma
The invention provides methods and materials for determining a prognosis for myeloma and myeloma-disposed ...
|
| 2002-074 |
|
Diagnostics |
Antibiotic Impregnated Peripherally Inserted Central Catheters (PICC's) with Continuous Central Venous Oximetry
A peripherally inserted central catheter includes three lumens that communicate with its proximal end. A ...
|
| 2002-077 |
None
|
Therapeutics |
Reducing the Gliding Resistance by Modification of Tendon Surface
Method to reduce gliding resistance and adhesion of tendon after tendon surgery by physical, chemical and ...
|
| 2002-095 |
None
|
Medical Devices |
Screw Hole Repair Device/Technique
Device and method for filling and repairing holes in bone after removal of screws or drilling; prevents ...
|
| 2002-098 |
None
|
Research Tools |
An Auto-regulated Doxycycline-inducible FIV-based Lentiviral Vector
This invention allows 1) inducible and regulated expression of a gene of interest from an integrated feline ...
|
| 2002-103 |
Pending
|
Electronic Devices |
Transmission Matrix De-embedding/Two-Tier Calibration Methods for Vector Network Analyzer (VNA) Measurement
We present a method for performing de-embedding (or equivalently, second-tier calibration) of vector network ...
|
| 2002-111 |
|
Software |
A Method and Apparatus for Disambiguation of Acronyms and Abbreviations
Systems and methods for disambiguating acronyms and abbreviations in written medical text.
...
|
| 2002-115 |
None
|
Research Tools |
2B7: A Chinese Hamster Ovary Cell Line Expressing High Levels of Human Amyloid Beta Protein Precursor
This cell line is a stably transfected Chinese hamster ovary (CHO) cell line. It is transfected with the ...
|
| 2002-116 |
None
|
Research Tools |
H4 wt APP Cells (H4 Cell Line)
H4 cell line stably transfected with an APP695wt clone in the pCDNA3 vector....
|
| 2002-126 |
|
Diagnostics |
Sulfotransferase (SULT) 2B1 Pharmacogenetics
The activity of the gene product is Sulfate conjugation. Several non-synonymous CSNPs have been discovered ...
|
| 2002-127 |
Pending
|
Diagnostics |
Measurement of Lymphocyte Receptor Diversity Using a Gene Chip
Immune competence is thought to be related to lymphocyte receptor diversity. There is currently no reliable ...
|
| 2002-131 |
None
|
Software |
Activity Monitoring Software
For corporate use. This product allows monitoring of activity on a workstation. This activity includes all ...
|
| 2002-141 |
Pending
|
Software |
Mayo Image Studio
Mayo Image Studio is an integrated PACS solution conmprising MayoImageX (A Dicon-based toolkit for image ...
|
| 2002-148 |
None
|
Diagnostics |
Rapid Asthma Kit (Rapid EDN Kit) by Immunochromatography
No commercial rapid diagnostic kits for asthma and allergic diseases are currently available. We are ...
|
| 2002-151 |
Pending
|
Diagnostics |
Functionally Relevent Genetic Polymorphisms in the Human Sulfotransferase (SULT) 1A3 Gene
SULT1A3 is involved in the sulfation of Dopamine,other catechol monoamines, serotonin, and Troglitazone. It ...
|
| 2002-152 |
|
Diagnostics |
Functionally Relevant Polymorphisms in the Human Phenylethanolamine N-Methyltransferase (PNMT) Gene
PNMT is the terminal enzyme in catecholamine biosynthesis and catalyses the synthesis of epinephrine from ...
|
| 2002-165 |
Pending
|
Software |
Automatic Identification of Patient Medication Status from Free Text of Clinical Documents
The invention comprises a method and apparatus for automatic identification patient status with respect to ...
|
| 2002-167 |
Pending
|
Medical Devices |
MRI Receiver Coil with Transmit Only Sections Designed to Reduce Artifacts
An RF coil with added coils which transmit only to reduce artifactual signals due to flow or poor magnet ...
|
| 2002-179 |
Pending
|
Medical Devices |
|
