Nonisotopic Measurement of GFR using Conray (iothalamic acid)

Reference #:

MMV-95-159

Inventors/Contributors

David M. Wilson, M.D., Jan H. Bergert, James P. Landers, Ph.D., Robert R. Liedtke

Description

A method to determine glomerular filtration rate (GFR) employing capillary electrophoresis to measure the concentration of non-labeled iothalamic (Conray) acid salt in urine and blood samples. [American Journal of Kidney Diseases, Vol. 30, No. 5 (November), 1997: pp 646-652] [Electrophoresis 1997, 18, 1827-1835] This is a simpler, less expensive method for the measurement of GFR. No need to be concerned with patient isotope exposure or the costs of isotope maintenance and disposal. Correlates highly with the standard I125 method. Possible to make kits.

Patent Status

	U.S. Patent Number 5,989,198 Issued November 23, 1999