Fluorescent In Situ Hybridization (FISH) Probe Development to Detect Immunoglobulin Light Chains Kapa (IGK) and Lambda (IGL) Translocations

Reference #:

2005-072

Inventors/Contributors

Ellen D. Remstein M.D., Richard R. Einerson

Description

Lymphoma, the cancer to the lymph glands and lymphocytes develop as a consequence of acquired genetic/chromosomal changes. In clinical practice identification of these genetic changes are critical in diagnosis and treatment of lymphoma patient. We have developed fluorescent in situ hybridization (FISH) for two targets frequently involved in lymphoma development. We believe that these probes will improve diagnosis of lymphoma as well as lead to identification of new genetic alterations important in lymphoma development.

Patent Status

Pending