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Reference #:
2007-005
Inventors/Contributors
Richard M. Weinshilboum M.D., Yuan Ji, Janet E. Olson Ph.D., Jianping (Jessica) Zhang, Linda L. Pelleymounter, Zachary S. Fredericksen, Vernon (Shane) S. Pankratz Ph.D., James N. Ingle M.D., Michelle A.T. Hildebrandt, Liewei Wang M.D., Ph.D., Irene Moon
Description
Two single nucleotide polymorphism (SNPs) within the COMT gene have been identified as potential biomarkers for the risk of developing breast cancer. After, genotyping 750 breast cancer samples and 750 control samples, the two SNPs were associated with an approximate 40% decrease in risk of breast cancer in pre-menopausal women. If the results can be replicated, these SNPs would be useful biomarker in a diagnostic test that could be used alone or in a panel of other biomarkers to identify pre-menopausal women at risk for developing breast cancer.
Patent Status
Pending |
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Contact
Leif R. Nelson, Licensing Manager
nelson.leif@mayo.edu
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Mayo Foundation for Medical Education and Research
Office of Technology Commercialization
Centerplace 4
200 First Street SW
Rochester, MN 55905
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Phone: (507) 266-0820
Fax: (507) 284-5410
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