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Mayo Clinic Technology
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A New Treatment for Atrial Fibrillation - A Transesophageal High Frequency Pacing Algorithm

Reference #:

2000-075

Inventors/Contributors

Paul A. Friedman, M.D., Naser M. Ammash, M.D., Charles J. Bruce, M.D., James B. Seward, M.D.

Description

In the past, the transesophageal echo probe has been used exclusively as a diagnostic tool. However, the probe's position within the esophagus in close proximity to the heart permits the delivery of new therapeutic interventions. this invention entails the addition of electrodes to the probe to permit delivery of two therapies: 1) Low energy high frequency pacing to painlessly terminate atrial fibrillation - pacing of the left atrium can be performed from within the esophagus due to the juxtaposition of these two structures. The use of high frequency burst pacing from within the esophagus has no precedent. Additionally, a new rate-adaptive pacing algorithm is described; 2) Cardioversion from within the esophagus by mean of a large surface area electrode limited precedence for transesophageal cardioversion exists. However, a custom biphasic waveform, designed to increase effectiveness and limit pain is described in this report. This may permit shock delivery without general anesthesia.

Patent Status

Pending

Contact

Tim D. Argo, Licensing Manager
targo@mayo.edu

Mayo Foundation for Medical Education and Research
Office of Technology Commercialization
Centerplace 4
200 First Street SW
Rochester, MN 55905

Phone: (507) 284-1839
Fax: (507) 284-5410