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Reference #:
1997-112
Inventors/Contributors
Sandra J. Gendler, Ph.D., Gerald Rowse, Ph.D.
Description
An inbred strain of transgenic mice that show tissue-specific expression of the human MUC1 gene. These animals express a form of the human MUC1 gene which codes for the core protein of a mucin expressed by glandular epithelia and carcinomas which develop from these tissues. The core protein is underglycosylated in these cancers and therefore represents a possible target for immunotherapy. These transgenic animals form the basis for the development of preclinical models for evaluations of novel cancer therapies.
Patent Status
None |
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Contact
Julie A. Henry, Licensing Manager
henry.julie@mayo.edu
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Mayo Foundation for Medical Education and Research
Office of Technology Commercialization
Centerplace 4
200 First Street SW
Rochester, MN 55905
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Phone: (507) 266-4585
Fax: (507) 284-5410
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