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Mayo Clinic Technology
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HLA-DR3.Abo Transgenic Mice

Reference #:

2000-064

Inventors/Contributors

Chella S. David, Ph.D.

Description

We developed an HLA-DR3.Abo mouse by introducing the DR3 transgene into a H2Abo mouse, class II negative strain, by mating with BIO.M-DRB1*0301 mice. Experimental autoimmune thyroiditis (EAT) is induced in these mice when immunized with either MTg or HTg.

Patent Status

None

Contact

Julie A. Henry, Licensing Manager
henry.julie@mayo.edu

Mayo Foundation for Medical Education and Research
Office of Technology Commercialization
Centerplace 4
200 First Street SW
Rochester, MN 55905

Phone: (507) 266-4585
Fax: (507) 284-5410