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Reference #:
2001-023
Inventors/Contributors
Todd E. Golde M.D., Eileen M. McGowan Ph.D., Pritam Das Ph.D.
Description
A novel expression system has been developed that selectively expresses ABeta40 or ABeta42 in the secretory pathway. This system enables expression of high levels of specific ABeta peptides. Such a system has been used to develop animal models that critically determine the pathogenicity of individual ABeta peptides. In addition, the system may have general utility as a means of expressing high-level of small peptides in the secretory pathway of many organisms.
Patent Status
Pending |
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Contact
Nathan L. Stacy, Licensing Manager
stacy.nathan@mayo.edu
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Mayo Foundation for Medical Education and Research
Office of Technology Commercialization
Centerplace 4
200 First Street SW
Rochester, MN 55905
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Phone: (507) 538-1652
Fax: (507) 284-5410
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