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Mayo Clinic Technology
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52KO Mouse Line

Reference #:

2004-109

Inventors/Contributors

David F. Smith, Ph.D., Joyce Cheung-Flynn, Ph.D.

Description

This invention is a mouse line in which we disrupted the gene for FKBP52, a protein component of steroid receptor complexes. The animals are reproductively compromised. These animals can be helpful in screening for environmental compounds and drugs that might bind FKBP52 and alter FKBP52-dependent processes. Of particular interest will be compounds that may promote defects in sexual differentiation and development.

Patent Status

None

Contact

Julie A. Henry, Licensing Manager
henry.julie@mayo.edu

Mayo Foundation for Medical Education and Research
Office of Technology Commercialization
Centerplace 4
200 First Street SW
Rochester, MN 55905

Phone: (507) 266-4585
Fax: (507) 284-5410