|
Reference #:
2005-107
Inventors/Contributors
Todd E. Golde, M.D., Thomas B. Ladd, Thomas L. Kukar, Ph.D., Marjorie J. Rochette, Karen R. Jansen-West, B.A.
Description
These cell lines express a protein (APP) that is cleaved to form the Amyloid beta protein (Abeta) deposited in Alzheimer's disease. Compared to other cell lines they produce extremely high levels enabling routine detection of even minor Abeta species (e.g. Abeta 42) in as little as 4-6 hours. Lysates and subcellular fractions from these cells can also be used for in vitro gamma-secretase activity assays.
Patent Status
None |
|
Contact
Susan L. Stoddard, Ph.D., Licensing Manager
sstoddard@mayo.edu
|
|
Mayo Foundation for Medical Education and Research
Office of Technology Commercialization
Centerplace 4
200 First Street SW
Rochester, MN 55905
|
Phone: (507) 284-1222
Fax: (507) 284-5410
|
|
|
