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Mayo Clinic Technology
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Assays for Detection of Malarial Signal Peptide Peptidase (SPP) Activity and Use in Identifying Novel Anti-Malarial Drugs

Reference #:

2006-100

Inventors/Contributors

Todd E. Golde M.D., Andrew C. Nyborg Ph.D., Craig W. Zwizinski Ph.D., Karen R. Jansen-West B.A., Thomas L. Kukar Ph.D., Thomas B. Ladd

Description

We have identified and synthesized a gene encoding a novel drug target in the malarial parasite (Plasmodium falciparum) genome that we refer to as malarial signal peptide peptidase (mSPP), and have developed a cell based assay that enables the detection of mSPP inhibitors that may be novel anti-malarial compounds.

Patent Status

None

Contact

Susan L. Stoddard, Ph.D., Licensing Manager
sstoddard@mayo.edu

Mayo Foundation for Medical Education and Research
Office of Technology Commercialization
Centerplace 4
200 First Street SW
Rochester, MN 55905

Phone: (507) 284-1222
Fax: (507) 284-5410