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Reference #:
2007-050
Inventors/Contributors
Diane F. Jelinek Ph.D., Mariana Ramirez-Alvarado Ph.D.
Description
The ALMC-1 and ALMC-2 cell lines were established from samples before and after peripheral blood stem cell transplant. Both cell lines secrete lambda light chains and these light chains have been shown to contain a beta structure, which is necessary for the configuration of amyloid. Therefore, this cell line provides a useful tool to study the underlying biology of amloidogenic light chains as well as the cell and molecular biology of malignant plasma cells observed in this rare monoclonal plasma cell disorder.
Patent Status
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Contact
Barbara A. Gamez Sims, Licensing Manager
gamezsims.barbara@mayo.edu
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Mayo Foundation for Medical Education and Research
Office of Technology Commercialization
MN BioBusiness Center
200 First Street SW
Rochester, MN 55905
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Phone: (507) 284-8171
Fax: (507) 284-5410
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