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Reference #:
2007-172
Inventors/Contributors
Peter J. Wettstein Ph.D., Nancy D. Borson Ph.D., Michael A. Strausbauch
Description
Thymus-derived (T) lymphocytes are important for controlling infections and cancer. The ability to carry out this function is determined in great part by the diversities of T lymphocyte populations which are, in turn, dependent on diversities of their antigen-specific receptors. This invention is a novel method for estimating the diversity of one subunit (beta) of T cell receptors (TcRs) of mice and humans and identifying beta subunits expressed by T cells that are over-represented at sites of T cell responses. This method is a significant improvement over existing assays in terms of speed, resolution, and volume of data.
Patent Status
Pending |
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Contact
Nathan L. Stacy, Licensing Manager
stacy.nathan@mayo.edu
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Mayo Foundation for Medical Education and Research
Office of Technology Commercialization
Centerplace 4
200 First Street SW
Rochester, MN 55905
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Phone: (507) 538-1652
Fax: (507) 284-5410
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