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Mayo Clinic Technology
.

Anti-SINA/SIAH Monoclonal Antibodies & Related Know-How

Reference #:

2008-016

Inventors/Contributors

Amy Hong Tang, Ph.D.

Description

Four mouse anti-SINA/SIAH monoclonal antibodies are available for licensing. Details are as follows. Two monoclonal antibodies against the SINA-C-terminal peptide (C-GC-FDTSIAQLFADNGNLGINVTISLV) (a 27-mer): (1) 8G7H12, (2) 4B4B6. Two monoclonal antibodies against the SINA-N-terminal peptide (SNKINPKRREPTAA-GGC) (a 17-mer): (1) 24E6H3, (2) 22B9B5. Reference: Rebecca L. Schmidt, Cheol Hong Park, Atique U. Ahmed, Justin H. Gundelach, Nanette R. Reed, Shen Cheng, Bruce E. Knudsen, and Amy H. Tang (2007) Inhibition of RAS-Mediated Transformation and Tumorigenesis by Targeting the Downstream E3 Ubiquitin Ligase Seven in Absentia Homologue, Cancer Res 2007 67: 11798-11810. doi: 10.1158/0008-5472.CAN-06-4471. The monoclonal antibodies have been used in Western blot and IHC. Species reactivity include Drosophila, pig, and human.

Patent Status

None

Contact

Catherine S. Koh, Licensing Manager
koh.catherine@mayo.edu

Mayo Foundation for Medical Education and Research
Office of Intellectual Property
Centerplace 4
200 First Street SW
Rochester, MN 55905

Phone: (507) 538-5096
Fax: (507) 284-5410