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Reference #:
2004-020
Inventors/Contributors
Richard A. Robb Ph.D., Ronald A. Karwoski, Jon J. Camp
Description
The CCAP program accurately and efficiently counts and analyzes cells in microscope images. A user interactively completes the followings steps: 1) Inhomogeneity correction: A digital filter is applied to correct for uneven illumination. 2) Calibration: A line is placed over an object of known size, usually a ruler, to determine the size of the image pixels. 3) Segmentation: The cells are interactively segmented using selected combinations of intensity thresholding, connected component analysis, and geometry constraints. 4) Measurement: The segmented cells are automatically counted and measurements made of area, diameter, volume mean diameter, standard deviation of diameter, mean volume, standard deviation of volume, heterogeneity and feature content. Histograms can be computed and displayed. 5) Report: The counts and measurements are saved along with the original images for subsequent review and use.
Patent Status
None |
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Contact
Steven T. McMaster, Licensing Manager
mcmaster.steven@mayo.edu
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Mayo Foundation for Medical Education and Research
Office of Technology Commercialization
Centerplace 4
200 First Street SW
Rochester, MN 55905
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Phone: (507) 266-0558
Fax: (507) 284-5410
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