The Use of Topical Anesthetics and Glucocorticoids in Combination as a More Effective Treatment for Eosinophil-Related Diseases

Reference #:

1996-123

Inventors/Contributors

Gerald J. Gleich, M.D., Jennifer L. Bankers-Fulbright, Ph.D.

Description

Studies have shown that treatment of purified human eosinophils with a combination of lidocaine and dexamethasone results in the synergistic inhibition of cytokine-mediated eosinophil survival, revealing site of action.This method can replace chronic glucocorticoid treatment, which is used in eosinophil-related diseases such as asthma.

Patent Status

	U.S. Patent Number 5,837,713 Issued November 17, 1998