Treatment of Eosinophil-Associated Pathologies by Signal Transduction Pathways

Reference #:

1999-087

Inventors/Contributors

Gerald J. Gleich, M.D., Jennifer L. Bankers-Fulbright, Ph.D., Scott O’Grady, (University of Minnesota)

Description

Compounds that modulate signal transduction such as lidocaine and other topical anesthetics for the treatment of asthma. A putative target of lidocaine, a compound that can replace glucocorticoids in the treatment of asthma, is part of a signal transduction pathway that may prove useful as a target for new treatments designed to treat asthma and other eosinophil-related disorders.

Patent Status

Pending