Potentiation of Immune Response Using Antibodies That Bind Dendritic Cells

Reference #:

2001-162

Inventors/Contributors

Larry. R. Pease, Ph.D., Loc T. Nguyen, Suresh Radhakrishnan, Moses Rodriguez, M.D., Daren R. Ure, Ph.D.

Description

An antibody has been discovered that binds mouse dendritic cells and potentiates their ability to induce antigen specific immune responses. This antibody has the ability to potentiate the immune response against protein or tumor antigens when administered without other adjuvants in vivo.

Patent Status

	U.S. Patent Number 7,052,694 Issued May 30, 2006