Superparamagnetic Cobalamin Analogs for the In Vitro and In Vivo Isolation, Localization and Destruction of Malignant Cells

Reference #:

2006-157

Inventors/Contributors

Douglas A. Collins M.D.

Description

A superparamagnetic nanoparticle of iron oxide is covalently bonded to Vitamin B12. The B-12-Iron oxide molecule will concentrate in the cancer cell through the B-12 receptor. Once inside the cell and alternating magnetic field is placed around a test tube (in vitro) or involved body part (in vivo) and magnetocytolysis (cancer cell death) occurs from heat generated vibration of the iron oxide in the magnetic field.

Patent Status

Pending