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Mayo Clinic Technology
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ABC-NP - - An Aquaretic and Natriuretic Peptide Without Vasodilatory Properties

Reference #:

2006-159

Inventors/Contributors

Horng H. Chen M.D., John C. Burnett Jr. M.D.

Description

The Natriuretic peptides (NP) are a naturally occurring family of peptides that increase salt excretion in the urine. One of the side effects of NP is decreasing blood pressure. We have created a designer peptide based on the amino acids sequence of the 3 existing NPs ANP, BNP and CNP which has the properties of salt and water excretion without the hypotensive effects of NP. The peptide ABC-NP may be potentially useful in help patients get rid of salt and water in heart failure, renal disease and liver disease.

Patent Status

Pending

Contact

Susan L. Stoddard, Ph.D., Licensing Manager
sstoddard@mayo.edu

Mayo Foundation for Medical Education and Research
Office of Technology Commercialization
Centerplace 4
200 First Street SW
Rochester, MN 55905

Phone: (507) 284-1222
Fax: (507) 284-5410